Your gift will help make a tremendous difference. But it’s important to stress that whatever diagnosis you may have, it’s not rare or weird to us at MD Anderson. Recently, treatment with temozolomide (TMZ) has shown promising results, although the lack of prospective trials limits assessment of benefit. Pancreatic NETs are subdivided into two main types, functional and non-functional. OncLive TV Releases 2 More Videos in Neuroendocrine Tumors Series. There are two targeted therapies that are used to treat advanced pancreatic NETs. Sinonasal neuroendocrine carcinoma (SNEC) and sinonasal undifferentiated carcinoma (SNUC) are types of sinonasal neuroendocrine tumor, together with olfactory neuroblastoma. If the tumor is large, either a pancreatoduodenectomy (or, more commonly, the Whipple procedure) or distal pancreatectomy may be used to remove the parts of the pancreas affected by the tumor. One study showed it reduced the rate at which neuroendocrine tumor progressed by 80%, so it’s a great option for neuroendocrine patients. This will not be our first time treating it. Several types of treatments are used for pancreatic NETs, including: The best way to treat pancreatic NETs that are contained within the pancreas is through surgery. The patient and the care team guide the specific treatment sequence based on their particular clinical situation as it evolves over time. Request an appointment at MD Anderson online or by calling 1-877-632-6789. Stage II: The tumor is 2 cm or larger and may have grown into nearby organs. Most neuroendocrine tumors occur in the lungs, appendix, small intestine, rectum and pancreas.There are many types of neuroendocrine tumors. Neuroendocrine tumors are extremely rare in the middle ear. A central pancreatectomy may be used if the tumor is small and confined to the pancreas. Because of this, these tumors often grow quite large before being diagnosed. The “neuro-” is more of a quirk of history. PMID: 32544169. Neurofibromatosis type 1 (NF1). IIIB: The tumor has spread to nearby lymph nodes, but has not spread to distant areas of the body. Hormones made by functional pancreatic NETs. The type of surgical procedure used varies depending on the type, size and location of the tumor. We searched our institution’s pathology files to identify patients treated from 1990 to 2015 who had lesions classified as middle ear adenomas, adenomatous tumors, adenomatous tumors with neuroendocrine … PCs are typically resistant to therapy and develop multiple recurrences despite surgery, radiotherapy and chemotherapy. MD Anderson’s strength is two-fold. Staging is a way of classifying cancer by how much disease is in the body and if it has spread. new treatments that cannot be found anywhere else. Due to our response to COVID-19, all blood donations at MD Anderson We’re currently leading clinical trials to find new pancreatic NET treatment options as well. Raj N, Chan J, Dasari A, Capanu M, Tang L, Reidy-Lagunes D. A Phase II Trial of LEE011 in Combination with Everolimus in the Treatment of Advanced Well Differentiated Neuroendocrine Tumors of Foregut Origin. Neuroendocrine tumors (NETs) originate from neuroendocrine cells which are located throughout the body. Investigator, 2007 - 2011. Al B. Benson III, MD (Medical Oncology) ... MD, FACS (Neuroendocrine-Carcinoid Tumor Surgery, Transplant Surgery, General Surgery) Kenner - SPECIALIST. The diagnosis of neuroendocrine carcinoma was suggested preoperatively from tissue biopsy in 59. It has not spread to nearby lymph nodes or distant areas of the body. Most of the FDA-approved treatments for neuroendocrine tumors were tested at MD Anderson through clinical trials. Neuroendocrine cervical cancer (NECC) is a rare and aggressive subtype of cervical cancer, accounting for less than 2% of cervical tumors. Once the staging classification is determined, it stays the same even if treatment is successful or the cancer spreads. Get details about our clinical trials that are currently enrolling patients. Background: Neuroendocrine carcinoma of the breast is a rare disease. So, they can experience symptoms for an average of five to seven years before finally receiving a neuroendocrine tumor diagnosis. Basically, neuroendocrine tumors are cancers that can develop anywhere endocrine cells are present. Jaffer Ajani, professor, department of gastrointestinal medical oncology, University of Texas MD Anderson Cancer Center, Houston. Clinical Fellowship, Surgical Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX: ... Low-grade neuroendocrine tumors arising in intestinal adenomas: evidence for alterations in the adenomatous polyposis coli/β-catenin pathway. MD Anderson has: MD Anderson doctors have played major roles in the approval of several pancreatic NET treatment options, including everolimus, octreotide, lanreotide, and Lu 177 dotatate. Our personalized portal helps you refer your patients and communicate with their MD Anderson care team. Now, all neuroendocrine tumors are considered malignant. I’d had mild bouts of diarrhea, gas, bloating and constipation for years. Choose from 12 allied health programs at School of Health Professions. But before my first appointment at MD Anderson, I began to experience sharp, intense pains while my mom and I were driving from Alabama to Texas for my grandmother’s funeral. Other patients in this group will exhibit hormonal symptoms, which point doctors in the direction of a tumor as the source. Member, Education Committee, The University of Texas MD Anderson Cancer Center, Houston, TX, 2018 - 2020. Pancreatic neuroendocrine tumors (NETs) form when the cells of the pancreas that make hormones multiply too rapidly. I became violently ill. The doctors inject the therapy, such as radioactive beads, into the blood vessels feeding the liver tumors. This type of radiation therapy uses an intravenous delivery of a radioactive drug called lutetium Lu 177 dotatate. Faculty Supervisor of Mid-Level Providers Program, The University of Texas MD Anderson Cancer Center Department of Gastrointestinal Medical Oncology, Houston, TX, 2003 - Present ... North American Neuroendocrine Tumor Society (NANETS) Executive Committee, Research Coordinator, 2007 - 2009. NANETS 2016, 2016. Because a neuroendocrine tumor arises from cells that produce hormones, the tumor can also produce hormones. That means our patients had access to them long before most people in the general population. Blood Donor Center locations are being held by appointment only. Some spread really easily. If you have questions about MD Anderson’s appointment process, our Learn about our graduate medical education residency and fellowship opportunities. And the sequencing of that treatment matters. These include conventional chemotherapy, hormone therapy and targeted therapies. The most common combinations are: Targeted therapies are a type of precision medicine. And we see plenty of rare and unusual cases even among neuroendocrine tumors. SWOG GI Committee. The highest 5-year survival rate reported in the surgical literature for patients who have undergone surgery for pancreatic cancer. (4)Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX, 77030, USA. Levels of this protein can be raised by many medications and conditions, including non-functional pancreatic NETs. information page may be the best place to start. The particular tests your doctor orders will be based on your symptoms. Many cases can be cured this way. The tumors were either pure NECa (10) o … NANETS 2016, 2016. Blood Donor Center locations are being held by appointment only. An unexpected neuroendocrine tumor diagnosis at age 22 was overwhelming for Lizzy Simonian. A neuroendocrine tumor can grow in spots like your pancreas, a gland in your belly. So a patient will go to the doctor, thinking they have a gallbladder issue, and it turns out to be a neuroendocrine tumor in the liver. Like our patients, we are extremely interested in the promise of immunotherapy to one day help our patients live longer and better lives. Our interventional radiologists also have several technologies they can use to control individual tumors, particularly in the liver. A biopsy, in which a piece of the suspected tumor is removed and then studied, is almost always required to definitively diagnose pancreatic NETs. Some neuroendocrine tumors … Studies have shown that they are more successful and have less risk when performed by doctors at major cancer centers with extensive experience. MD Anderson patients have access to clinical trials offering promising Solid neuroendocrine carcinoma of the breast was diagnosed by excision biopsy and histopathological analysis. Pancreatic NETs are rare and not frequently seen in most cancer centers. Find the latest news and information about pancreatic cancer in our Change the lives of cancer patients by giving your time and talent. This type of therapy was approved by the U.S. Food & Drug Administration in 2018. We tend to see neuroendocrine symptoms in two categories: How are neuroendocrine tumors usually diagnosed? However, it is important to discuss any of these symptoms with your doctor. They share overlapping clinical, radiological, and histopathological features, albeit with variability in behavior and prognosis between each other. Knowledge Center, including blog posts, articles, videos, news releases These include insulin, gastrin, glucagon, somatostatin, pancreatic polypeptide (PP) or vasoactive intestinal peptide (VIP). Chemotherapy drugs commonly used to treat pancreatic NETs include: Based on a patient’s ability to tolerate therapy, two or more of the chemotherapy drugs above are typically given in combination. Our surgeons are among the most experienced and skilled in the nation. Some pancreatic NETs grow so slowly that the risks of treating may outweigh the risks of not treating for a period of time. In some of the older systems for classifying neuroendocrine tumors, pathologists would describe them as either “benign” (non-cancerous) or “malignant” (cancerous), based on the appearance of the tumor cells under a microscope. This method uses a substance called octreotate, which attaches to most pancreatic NETs and can then be seen on imaging tests. Pancreatic NETs are rare and not frequently seen in most cancer centers. These tumors, previously called islet cell tumors, make up less than 5% of new pancreatic cancers. 24 Santos-Pinheiro F, Penas-Prado M*, Kamiya-Matsuoka C*, Waguespack SG, Mahajan A, Brown PD, Shah 25 KB, Fuller GN, McCutcheon IE. They fall into two categories. This treatment regimen is based on data from studying neuroendocrine lung tumors, since no studies have been done to date in neuroendocrine cervical tumors. These are procedures performed by specialized interventional radiologists. (Source: American Joint Committee on Cancer (AJCC) 2018 Staging Manual). One set is looking to build on the success of peptide receptor radionuclide therapy. The most … Non-functional pancreatic NETs do not produce large amounts of hormones. These surgical procedures are extremely complex, and studies have shown that the best outcomes occur when they are performed at a major cancer center by an experienced surgeon. MD Anderson researchers have led the development of novel treatment strategies, including targeting of mTOR (a protein) and angiogenesis (growth of new blood vessels) in neuroendocrine tumors (including carcinoid tumors). Primary neuroendocrine carcinoma of the vagina is a rare entity with only 25 previously reported cases in the literature. But we consider all of them cancer. James Yao MD, associate professor and deputy chair, Department of Oncology, University of Texas, MD Anderson Cancer Center, Houston. Surgery leads to neuroendocrine tumor diagnosis. Pathology was reviewed and tumors were categorized as small cell carcinoma (n = 22) or large cell neuroendocrine carcinoma (n = 16). What are neuroendocrine tumors, and where are they usually found? This treatment slows the growth of liver tumors and can also shrink them. MD Anderson’s large patient volume gives our doctors the opportunity to treat more pancreatic NETs than most centers. The prognosis of women with NECC is poor and there is no standardized therapy for this type of malignancy based on controlled trials. *both authors contributed equally. Houston, Texas - MD Anderson’s Gastrointestinal Center gives exemplary, customized carcinoid tumor care every step of the way.As one of the nation’s largest cancer centers, MD Anderson sees more patients with this complex type of cancer than most others, which translates into more successful outcomes for carcinoid tumors. Neuroendocrine Tumors Version 3.2017 — June 13, 2017 ... MD Anderson Cancer Center NCCN Jennifer Burns Deborah Freedman-Cass, PhD Ndiya Ogba, PhD NCCN Guidelines Panel Disclosures ¶ Surgery/Surgical oncology † Medical oncology ð Endocrinology ≠ Pathology Þ Internal medicine We have a dedicated team of doctors who are highly experienced treating this rare cancer. The patients ranged in age from 37 to 87 years (median, 57 y) and most commonly presented with vaginal bleeding. Neuroendocrine carcinoma (NECa) of the endometrium is an uncommon tumor. The Neuroendocrine Tumor Program at the University of Chicago Medicine (Multidisciplinary Center) Chicago - SPECIALIST. You just need to send them all of the pathology slides and (for a small fee-$250-I think) they will review them and write a report. And we are very happy to work together to find the best treatment plan for you. IIIA: The tumor has grown into nearby organs, such as the stomach, spleen, colon or adrenal gland, or into large blood vessels. Dr. Halperin is a medical oncologist and clinical investigator focused on the development of novel treatments for patients with neuroendocrine tumors (NETs), in addition to providing high-quality clinical care to patients with NETs and other... gastrointestinal cancers. Why choose MD Anderson for pancreatic neuroendocrine tumor care? This procedure removes only the small part of the pancreas affected by the tumor. First, we have specialists who care for patients with these tumors all day, every day. After meeting with Dr. Daniel Halperin, one of the leading neuroendocrine specialists in the country, I was convinced that MD Anderson was the right place for me. These operations are extremely complex. I was admitted to MD Anderson’s Emergency Center for a bowel obstruction on May 21, 2018. Because we believe that the right treatment at the right time by doctors who specialize in treating this complex disease offers patients the most benefit. These tests are more commonly used in pancreatic NET staging, rather than diagnosis. There are just shades of gray in terms of how aggressive they are. The B-Cell Lymphoma Moon Shot is revolutionizing the conventional medical research approach to rapidly translate findings into patient treatment options and develop personalized therapeutic strategies. In select cases, liver surgery can be used to remove liver metastases. The newest option is a type of systemic radiation called peptide receptor radionuclide therapy, or PRRT. Your gift will help make a tremendous difference. Log in to our secure, personalized website to manage your care (formerly myMDAnderson). Yes. Chemotherapy can be used to stop a tumor from growing, and to shrink larger tumors. They are distributed throughout the body, but the most common places for tumors to develop from them are in the lungs, small intestines and pancreas. Combination of mammography and sonography may be useful to improve the accuracy of diagnosis and early detection of neuroendocrine carcinoma of the breast. I learned I had a neuroendocrine tumor in February 2018. Less than a 1% mortality rate after surgery for pancreatic cancer. Non-functional NETs don’t produce hormones at a high enough level to cause noticeable symptoms. This is called enucleation. My neuroendocrine tumor diagnosis. If you’re diagnosed with a pancreatic NET, your doctor will determine the stage of the disease. Their symptoms are different than symptoms of pancreatic adenocarcinomas. Because of this, they cause noticeable symptoms. If you are ready to make an appointment, select a button on the right. The Lyda Hill Cancer Prevention Center provides cancer risk assessment, screening and diagnostic services. Blood tests are used to check the levels of these substances, which include: Many of the imaging tests and methods that are used to detect and biopsy pancreatic adenocarcinomas are used to diagnose pancreatic NETs. It can also happen in your stomach, intestines, or lungs. This helps the doctor plan the best way to treat your pancreatic NET. As part of our mission to eliminate cancer, MD Anderson researchers conduct hundreds of clinical trials to test new treatments for both common and rare cancers. As part of our mission to eliminate cancer, MD Anderson researchers conduct hundreds of clinical trials to test new treatments for both common and rare cancers. Hormone therapy can be used when surgery is not possible. Learn about clinical trials at MD Anderson and search our database for open studies. information page may be the best place to start. Then we get into the systemic treatments, which treat the cancer wherever it is in the entire body. Background: Neuroendocrine carcinoma of the cervix (NECC) is a rare variant of cervical cancer. Where you go first for treatment matters. Functional NETs produce very high amounts of hormones. If you have MEN2, you're more likely to get neuroendocrine tumors such as pheochromocytoma, medullary thyroid cancer, and parathyroid tumors. These tumors are named based on the type of hormone they overproduce. Why should patients come to MD Anderson for neuroendocrine tumor treatment? Choose from 12 allied health programs at School of Health Professions. What are pancreatic neuroendocrine tumor treatment options? About 12,000 people will be diagnosed with neuroendocrine tumors — sometimes called carcinoid tumors — each year. This drug delivers radiation by attaching to the tumor directly. Some grow slowly and some grow very quickly. When pancreatic NETs spread to the liver, liver-directed therapy can be used. Maybe it was picked up during a colonoscopy, or during an X-ray or CT scan for a broken bone. One example is everolimus, which James Yao, M.D., was studying as early as 2006 – six years before it was approved by the FDA. In this study, we present the clinicopathologic features of 25 such cases. Specialized Programs of Research Excellence (SPORE) Grants, Prevention & Personalized Risk Assessment, Office of Clinical Research Administration, Comparative Effectiveness Training (CERTaIN), Post Graduate Fellowship in Oncology Nursing, Professional Student Nurse Extern Programs, 9 things to know about neuroendocrine tumors. But, she says, “My MD Anderson care team helped change my outlook in the month I spent at the hospital.” Here’s how they put her at ease -- and how that care led her to work at MD Anderson. MD Anderson researchers were involved from proof-of-concept single institution phase II to multi-national phase III studies. The exact cause of pancreatic NETs is not known. Neuroendocrine tumors are cancers that begin in specialized cells called neuroendocrine cells. Many patients with neuroendocrine tumors have hormonal symptoms that get progressively worse. The most common diagnostic imaging method for pancreatic NETs is a CT scan. First, we have specialists who care for patients with these tumors all day, every day. The B-Cell Lymphoma Moon Shot is revolutionizing the conventional medical research approach to rapidly translate findings into patient treatment options and develop personalized therapeutic strategies. This means that these tumors can grow or spread without causing noticeable symptoms. Among the shortest average length of hospital stay after surgery for pancreatic cancer. The data we have right now suggests it’s not easy to use immunotherapy against neuroendocrine tumors, but we are starting to look at more combinations of agents and trying to figure out how to break the immune tolerance of these tumors. Unusual levels of certain substances may indicate the presence of a pancreatic NET. While the name “neuroendocrine” implies that these tumors involve both nerve cells and hormones, they are mainly thought to come from endocrine cells. Non-functional pancreatic NETs are more common than functional pancreatic NETs. Cancer Treatment Centers of America: "Neuroendocrine Tumors." And we see plenty of rare and unusual cases even among neuroendocrine tumors. Comparative genomics of high grade neuroendocrine carcinoma of the cervix. That is over 6% lower than the national average. Several other specific tests can be used to help diagnose functional pancreatic NETs. Sometimes the surgeon can remove the tumor without removing any part of the pancreas. Specialized Programs of Research Excellence (SPORE) Grants, Prevention & Personalized Risk Assessment, Office of Clinical Research Administration, Comparative Effectiveness Training (CERTaIN), Post Graduate Fellowship in Oncology Nursing, Professional Student Nurse Extern Programs, Multiple endocrine neoplasia, type 1 (MEN1), Pain in the abdomen or back, and possibly a lump in the abdomen, Jaundice, or yellowing of the skin and whites of the eyes. This webpage focuses only on pancreatic NETs. Learn about clinical trials at MD Anderson and search our database for open studies. We are hard at work in the clinic and the laboratory to figure out the best way forward. Are there any clinical trials currently available for patients with neuroendocrine tumors? So our neuroendocrine tumor specialists have a lot of individual and collective experience deciding on which … If you have questions about MD Anderson’s appointment process, our Stage III: The tumor has grown into nearby organs or blood vessels, or spread to the lymph nodes. Because they have gone undiagnosed or misdiagnosed for so long, it can be very hard for some patients to rebuild a trusting relationship with their medical team. and more. This most commonly occurs in the liver. Anything else you want newly diagnosed patients and their families to know about neuroendocrine tumors? Tag: MD Anderson. This therapy uses somatostatin analogues, such as octreotide or lanreotide, to slow a tumor’s growth. Survival Trends in Neuroendocrine Tumors and Associated Prognostic Factors. Neuroendocrine cells have traits similar to those of nerve cells and hormone-producing cells.Neuroendocrine tumors are rare and can occur anywhere in the body. When symptoms do occur, they can include: These symptoms do not always mean you have a pancreatic NET. We reviewed our institutional experience with middle ear adenomatous neuroendocrine tumors … Log in to our secure, personalized website to manage your care (formerly myMDAnderson). This stage is divided into IIIA and IIIB. What are the most common symptoms of neuroendocrine tumors? . For larger tumors or metastatic disease, MD Anderson is using combined chemotherapy and radiation, plus additional chemotherapy. Another is building on targeted therapies, and a third is focusing on immunotherapy. But scans and tests never showed anything unusual, so I was told … We reviewed our institutional experience with middle ear adenomatous neuroendocrine tumors (MEANTs). In some cases, somatostatin receptor imaging can be used to visualize pancreatic NETs. A neuroendocrine tumor (NET) is a rare type of tumor that arises from specialized body cells called neuroendocrine cells.These cells have traits of both nerve cells and hormone-producing cells, and release hormones into the blood in response to signals from the nervous system. Why are neuroendocrine tumors so challenging to treat? Peptide receptor radionuclide therapy (PRRT) was recently approved to treat somatostatin-receptor positive pancreatic NETs. What are pancreatic neuroendocrine tumor symptoms? We have a dedicated team of doctors who are highly experienced treating this rare cancer. Robert A. Ramirez, DO (Medical Oncology) But what exactly are these tumors, where are they typically found and are they cancerous? Symptoms of non-functional pancreatic NETs. 2 22 Pituitary carcinoma: The University of Texas MD Anderson Cancer Center 23 experience. MD Anderson will give you a second opinion based off of the pathology specimans. Most patients fall into one of two groups. Peptide receptor radionuclide therapy (PRRT), Fluorouracil (5-FU) with doxorubicin and streptozocin. But even when a neuroendocrine tumor has spread, surgery can still be useful in certain circumstances. High-grade NECC is associated with human papillomavirus (HPV) 18 and to a smaller extent type 16. Several other diagnostic tests may also be used to identify, locate and stage (determine extent of) the disease. # EndCancer © 2021 The University of Texas MD Anderson Cancer Center. Stage IV: The tumor has spread to distant areas of the body, and may or may not have grown to nearby areas outside of the pancreas or spread to nearby lymph nodes. In previous reports, these tumors have not been distinguished from primary neuroendocrine carcinoma of the skin (Merkel cell carcinoma). There’s no “typical” treatment sequence for neuroendocrine tumors. Hormone therapy can also be used to reduce the level of hormones produced by functional pancreatic NETs. These tumors are occasionally associated with genetic syndromes, such as: If you’re concerned about genetic or hereditary syndromes that may cause pancreatic NETs, we offer advanced genetic testing to let you know your risk. This can apply to some tumors contained within the pancreas as well some cases of metastatic disease. Why should patients come to MD Anderson for neuroendocrine tumor treatment? © 2021 The University of Texas MD Anderson Cancer Center. Your gift will help support our mission to end cancer and make a difference in the lives of our patients. By the time they have an accurate diagnosis, they have often already moved from doctor to doctor seeking help, hearing over and over, “I don’t do this very often, so it’s not my strength,” or “What you have is rare and very weird.”. This chapter focuses on low- to intermediate-grade gastroenteropancreatic NETs (GEP-NETs), although the term neuroendocrine tumor also denotes diseases such as small cell carcinoma, medullary thyroid carcinoma, neuroblastoma, and Merkel cell tumor. How are pancreatic neuroendocrine tumors diagnosed? 3 percent (16/27) of patients evaluable. The Lyda Hill Cancer Prevention Center provides cancer risk assessment, screening and diagnostic services. Neuroendocrine tumors (NETs) originate from enterochromaffin cells distributed throughout the body. Background: Pituitary carcinoma (PC) is an aggressive neuroendocrine tumor diagnosed when a pituitary adenoma (PA) becomes metastatic. Case Report: We present a 65-yearold female patient with an enlarged breast mass within 2 months. So our neuroendocrine tumor specialists have a lot of individual and collective experience deciding on which treatments to use and in what order. PLoS One 15(6):e0234505, 2020. e-Pub 2020. IIA: The tumor is less than 4 cm and is contained within the pancreas. Due to our response to COVID-19, all blood donations at MD Anderson Endocrine cells help regulate various body functions, such as growth, reproduction and metabolism. We spoke with neuroendocrine tumor specialist Daniel Halperin, M.D., to learn more. Neuroendocrine tumors are extremely rare in the middle ear. April 1, 2013. Whatever diagnosis you may have, it’s not rare or weird to us. They are divided into low-grade and high-grade tumors. AB - Objective The purpose of this study was to describe the X-ray features of the neuroendocrine carcinoma (NEC) of breast to … This may reduce negative side effects of these tumors. This chapter focuses on low-to intermediate-grade NETs of the gastrointestinal tract, though the term neuroendocrine tumor can also denote other diseases such as small-cell carcinoma of pulmonary and extrapulmonary origins, thyroid medullar carcinoma, neuroblastoma, and Merkel cell tumors. Find information and resources for current and returning patients. Change the lives of cancer patients by giving your time and talent. They’re also diagnosed and treated differently. Neuroendocrine cervical cancer (NECC) is a rare and aggressive subtype of cervical cancer, accounting for less than 2% of cervical tumors. Some seek help for symptoms, such as pain due to metastatic disease. IIB: The tumor is larger than 4 cm and is either still contained within the pancreas or has grown into the small intestine or bile duct. (4)Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA. In these cases, careful observation can be used as a treatment strategy. There are literally hundreds of possibilities. Hum Pathol 45(10):2051-8, 2014. e-Pub 2014. Our personalized portal helps you refer your patients and communicate with their MD Anderson care team. They slow or stop the growth of cancer by targeting specific features on cancer cells.

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